Axelle Loriot
Senior Investigator & BIOINFO Core Facility Manager
Bioinformatics - BIOINFO
Axelle Loriot
Institut de Duve
Avenue Hippocrate, 74 - B1.75.04
1200 Bruxelles
BIOINFO core facility, managed by Dr Axelle Loriot, offers technical and methodological support in Bioinformatics, ranging from project drafting to data analysis results interpretation.
Equipment
HPC servers at the de Duve Institute
Offered service
Platform services:
- Conception or drafting of projects and the planning of experimental designs
- Analyses of omics data obtained from high-throughput technologies such as:
- Transcriptomics (data processing, bulk RNAseq, miRNAseq, scRNAseq, spatial transcriptomics)
- Proteomics (raw mass spectrometry data processing, quantitative proteomics data analysis)
- Epigenomics (WGBS, Epic array, Chip seq)
- Metabolomics (statistical analysis)
- Metagenomics
- Genomics
- Assistance in the exploitation of public databases (TCGA, GTEx, CCLE, ENCODE, …)
- Development of algorithms and dedicated softwares
Pricing
The rates depend on the type of omics data and on the complexity of the analyses. The pricing usually includes planning of experimental design, raw data processing, analyses, presentation and explanations of the results, generation of publication quality figures, … until to the preparation of the material and methods section of your research paper.
Bioinformatics trainings
The platform organizes Bioinformatics trainings for researchers. The aim is to facilitate access to specialized programs such as R and introduce them to high-throughput data analysis.
Team
Academic supervisor
Specific HIF-2α (Hypoxia-Inducible Factor-2) Inhibitor PT2385 Mitigates Placental Dysfunction In Vitro and in a Rat Model of Preeclampsia (RUPP).
Colson A, Depoix CL, Lambert I, Leducq C, Bedin M, De Beukelaer M, Gatto L, Loriot A, Peers de Nieuwburgh M, Bouhna K, Baldin P, Hubinont C, Sonveaux P, Debiève F.
Hypertension (2023) 80(5):1011-1023.
Senescence and senotherapies in biliary atresia and biliary cirrhosis.
Jannone G, Bonaccorsi Riani E, de Magnée C, Tambucci R, Evraerts J, Ravau J, Baldin P, Bouzin C, Loriot A, Gatto L, Decottignies A, Najimi M, Sokal EM.
Aging (Albany NY). (2023) 15(11):4576-4599
Tumour immune rejection triggered by activation of α2-adrenergic receptors.
Zhu J, Naulaerts S, Boudhan L, Martin M, Gatto L, Van den Eynde BJ.
Nature (2023) 618(7965):607-615
BRAFV600E Induction in Thyrocytes Triggers Important Changes in the miRNAs Content and the Populations of Extracellular Vesicles Released in Thyroid Tumor Microenvironment.
Delcorte O, Spourquet C, Lemoine P, Degosserie J, Van Der Smissen P, Dauguet N, Loriot A, Knauf JA, Gatto L, Marbaix E, Fagin JA, Pierreux CE.
Biomedicines (2022) 10(4):755
Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells.
Assi M, Achouri Y, Loriot A, Dauguet N, Dahou H, Baldan J, Libert M, Fain JS, Guerra C, Bouwens L, Barbacid M, Lemaigre FP, Jacquemin P.
Cancer Res (2021) 81(10):2679-2689
Avenue Hippocrate 75 - 1200 Brussels - BELGIUM
VAT : BE0423 837 837
Tel : +32 2 764 75 50